Newest Homes for Sale in Sikeston, MO

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  /57

  $279,900

  • 5 Beds
  • 2 Baths
  • 3,495 Sq Ft

  303 Dorothy St, Sikeston, MO 63801

  Welcome to 303 Dorthy an amazing Victorian-style home full of character and historical charm. This spacious property features 5 bedrooms and 2 bathrooms, Also coming with 3,495 sqft offering plenty of room for comfortable living. The home has a warm, inviting feel throughout and includes a beautiful wrap-around porch perfect for relaxing. Situated on a large lot, this property also comes with an

  Jakahran Johnson EDGE Realty ERA Powered

  303 Dorothy St, Sikeston, MO 63801
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  /12

  $124,500

  • 2 Beds
  • 2 Baths
  • 1,152 Sq Ft

  1510 E Kathleen St, Sikeston, MO 63801

  Discover this single-story residence in Sikeston, offering 1,152 square feet of living space on a level 0.25-acre lot. This home features a fresh roof in recent shingling and comes equipped with a dishwasher, refrigerator, washer, and dryer. Inside, you will find a functional layout and a public water/sewer connection. The interior serves as a blank canvas, ready for your custom flooring and

  John David USRealty.com, LLP

  1510 E Kathleen St, Sikeston, MO 63801
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  /20

  $169,900

  • 3 Beds
  • 2 Baths
  • 1,724 Sq Ft

  710 N Ranney St, Sikeston, MO 63801

  This charming all-brick home sits in one of the area’s most desirable neighborhoods, offering timeless character and comfortable living throughout its 1,720 square feet. Built in 1950, the home showcases beautiful original wood floors that add warmth and authenticity to each room. The inviting living area features a cozy gas fireplace, creating the perfect spot to unwind at the end of the day.

  Delmar Alcorn C. Lawrence Realty LLC

  710 N Ranney St, Sikeston, MO 63801
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  /19

  $194,500

  • 3 Beds
  • 1.5 Baths
  • 1,876 Sq Ft

  215 Missouri Ave, Sikeston, MO 63801

  This well-maintained brick home offers a warm and inviting layout with 1,862 square feet of comfortable living space. Inside, you’ll find three bedrooms and one and a half baths, along with a bright kitchen where all appliances remain, including a convenient breakfast bar that opens the space for easy gatherings. The home features not one but two-family rooms, giving you the flexibility to create

  Delmar Alcorn C. Lawrence Realty LLC

  215 Missouri Ave, Sikeston, MO 63801
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  /11

  $731,250

  • Land
  • 22.5 Acres
  • $32,500 per Acre

  0 E Salcedo Rd, Sikeston, MO 63801

  SUBDIVISION DEVELOPMENT OPPORTUNITY. Tracts of this caliber rarely become available. This prime corner tract is located at the corner of E Salcedo Road and N Ingram Road, across from the Sikeston Recreational Complex. It is inside the city limits of Sikeston, not in a flood zone, and is an exceptional setting for a residential subdivision. The combination of location, visibility, and proximity to

  Tim Merideth Century 21 Premiere Realty

  0 E Salcedo Rd, Sikeston, MO 63801
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  /20

  $120,000

  • 2 Beds
  • 1 Bath
  • 1,002 Sq Ft

  2012 Ables Rd, Sikeston, MO 63801

  Welcome to this cozy and inviting 2-bedroom, 1-bath home in Sikeston. It features a comfortable layout with a bright living spaced and functional kitchen. The attached carport adds convenience, while the spacious backyard offers plenty of room to relax, entertain, or enjoy the outdoors.

  Ashlyn Sutton Century 21 Premiere Realty

  2012 Ables Rd, Sikeston, MO 63801
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  /23

  $275,000

  • 3 Beds
  • 2 Baths
  • 1,946 Sq Ft

  829 Plantation Blvd, Sikeston, MO 63801

  Welcome to this beautiful 3-bedroom, 2-bath home located in a desirable Sikeston neighborhood! Step inside to an inviting open floor plan that seamlessly connects to the living, dining and kitchen areas-perfect for both everyday living and entertaining. The vaulted ceilings add an airy, spacious feel, while natural light fills the home throughout. The kitchen offers great functionality and flows

  Pam Dannenmueller EDGE Realty, ERA Powered

  829 Plantation Blvd, Sikeston, MO 63801
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  /8

  $90,000

  • Land
  • 3 Acres
  • $30,000 per Acre

  2215 State Highway U, Sikeston, MO 63801

  Imagine a quiet country setting just a short drive to Interstate 55 with only 15 minutes to both Cape Girardeau & Sikeston. This property is not only located in Kelly School district but situated directly on a paved state road with access to county water. This cleared lot is ready for you to build your dream home on with a lot of space to stretch out and enjoy a peaceful country setting.

  Kyla Evans Paul Kitchen & Associates

  2215 State Highway U, Sikeston, MO 63801
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  /21

  $249,000 New Construction

  • 3 Beds
  • 2 Baths
  • 1,300 Sq Ft

  50 Byrd Dr, Sikeston, MO 63801

  Welcome to this stunning NEW construction home, thoughtfully designed with modern living in mind. This beautifully crafted residence features an open-concept floor plan that seamlessly connects the living, dining, and kitchen areas—perfect for both everyday living and entertaining. Offering 3 spacious bedrooms and 2 full bathrooms, the home provides comfort and functionality for a variety of

  Lawren McMullan EDGE Realty, ERA Powered

  50 Byrd Dr, Sikeston, MO 63801
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  /60

  $475,000

  • 4 Beds
  • 4 Baths
  • 3,833 Sq Ft

  118 Greenbriar Dr, Sikeston, MO 63801

  Located on a desirable corner lot in one of the most sought-after neighborhoods on the north end of Sikeston, this meticulously maintained custom-built home (1988) offers exceptional space, craftsmanship, and distinctive features rarely found in today’s homes. With approximately 3,800 square feet of living space, the home features 4 bedrooms and 4 bathrooms, providing plenty of room for

  Stephanie Anderson SMG Realty

  118 Greenbriar Dr, Sikeston, MO 63801
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  /2

  $400,000

  • Land
  • 2.63 Acres
  • $152,091 per Acre

  109 Stallcup Dr, Sikeston, MO 63801

  Over 2.5 acres of commercial property located in the heart of Sikeston's booming retail and hospitality area. Just a block from Wal-Mart Supercenter, 2 new hotels, shopping and restaurants, and a half mile to the intersection of US Highways 60 & 61. This is a premium location at an outstanding price.

  Tim Merideth Century 21 Premiere Realty

  109 Stallcup Dr, Sikeston, MO 63801
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  /34

  $210,000

  • 4 Beds
  • 2 Baths
  • 1,922 Sq Ft

  406 Lynn St, Sikeston, MO 63801

  Located in the highly sought-after Mini Farms subdivision just outside Sikeston, this beautifully remodeled 4-bedroom, 2-bath home on 1.84 acres offers the perfect combination of modern updates and country-style living with convenient access to town. The home was completely remodeled in 2025 and includes major system updates such as new gas heat and air, a new gas tankless water heater, and an

  Lynsey Perry Silverthorn Realty, LLC

  406 Lynn St, Sikeston, MO 63801
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  /11

  $99,900

  • 3 Beds
  • 1 Bath
  • 1,237 Sq Ft

  303 Greer Ave, Sikeston, MO 63801

  Are you ready for a small home in Sikeston? You can sit on the covered, front porch and enjoy a morning cup of coffee while watching others out and about! This Bungalow-style home boasts of 3 bedrooms, 1 bathroom, an eat-in kitchen, a covered carport in back yard all located on a corner lot. The kitchen has several cabinets, an island along the wall, and a range and a dishwasher included. It's

  Scott Harrison Delta Realty, LLC

  303 Greer Ave, Sikeston, MO 63801
• 

  

  /19

  $184,900

  • 4 Beds
  • 2 Baths
  • 1,914 Sq Ft

  410 Hux St, Sikeston, MO 63801

  Discover your dream home in this delightful 4-bedroom, 2-bath ranch that perfectly blends comfort and style. Nestled on a serene street, this inviting residence features a spacious front porch, ideal for sipping morning coffee or enjoying evening sunsets. Step inside to find a bright and airy layout that welcomes you with warmth and charm.The heart of the home boasts an open living area,

  Brandon Kielhofner EPM Real Estate

  410 Hux St, Sikeston, MO 63801
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  /12

  $237,000

  • 2,262 Sq Ft

  203 N Kingshighway St Unit A & B, Sikeston, MO 63801

  Lisa Russell EXP Realty LLC

  203 N Kingshighway St Unit A & B, Sikeston, MO 63801
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  /17

  $255,000

  • 4 Beds
  • 2 Baths
  • 2,347 Sq Ft

  209 Aletha Dr, Sikeston, MO 63801

  Looking for a home outside the city limits in a great neighborhood? This property offers the space, yard, and location you’ve been looking for. This 4 bedroom, 2 bathroom home has been recently remodeled and features several major updates including a newer roof, new hot water heater, new septic system, updated kitchen. The home offers an open concept layout between the living area and kitchen,

  Hudson Kuykendall EDGE Realty ERA Powered

  209 Aletha Dr, Sikeston, MO 63801
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  /9

  $27,500

  • 2 Beds
  • 1 Bath
  • 1,116 Sq Ft

  405 Branum St, Sikeston, MO 63801

  Investor Special in Sikeston! Opportunity awaits at 405 Branum St. This property has been partially gutted and is ready for your vision to bring it back to life. Major demo work has already been completed, saving you time and upfront labor. Whether you’re looking for your next fix-and-flip project, rental property, or long-term hold, this is a blank canvas with serious upside potential.

  Jonathan Adams Keller Williams Realty West

  405 Branum St, Sikeston, MO 63801
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  /9

  $100,000

  • 2 Beds
  • 1 Bath
  • 1,030 Sq Ft

  448 Crowe St, Sikeston, MO 63801

  TWO BEDROOM HOUSE LOCATED ON A LARGE CORNER LOT WITH 3 EXTRA VACANT LOTS INCLUDED, ALONG WITH TWO DETACHED SHOPS

  Tony McDonald McDonald Realty

  448 Crowe St, Sikeston, MO 63801
• 

  

  /22

  $275,000

  • 3 Beds
  • 2 Baths
  • 2,147 Sq Ft

  2011 State Highway H, Sikeston, MO 63801

  This one checks a LOT of boxes!3 beds. 2 baths. Kelly School District. Updated kitchen. Finished basement with a full bath. Big backyard. 2-car garage.And yes — the expensive stuff is already done. We're talking a recently remodeled basement and updated kitchen that actually makes you want to cook in it. No big projects waiting for you on move-in day. Just a solid, move-in ready home in

  Amber Prasanphanich EDGE Realty ERA Powered

  2011 State Highway H, Sikeston, MO 63801
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  /20

  $172,900

  • 3 Beds
  • 2 Baths
  • 1,382 Sq Ft

  10 Dement Rd, Sikeston, MO 63801

  This 3 bedroom, 1 & 3/4 bath home features a split bedroom floor plan and an eat-in kitchen, with a two car garage. Outside features an RV electrical hookup with parking, a nice rear patio, large yard, a shed and a kennel. If you area looking for space, check this one out. It is just out of town in Ridgeview Acres with friendly neighbors and feels like country living. The backyard is large enough

  allen basham EXP Realty, LLC

  10 Dement Rd, Sikeston, MO 63801
• 

  

  /11

  $127,500

  • 2 Beds
  • 1 Bath
  • 910 Sq Ft

  628 Moore Ave, Sikeston, MO 63801

  This charming bungalow in Sikeston's historic district has been beautifully updated and is ready for its new owner. Featuring 2 bedrooms and 1 bath, it's the perfect home for first-time buyers or anyone looking to downsize. Conveniently located withing walking distance to the YMCA and local grocery stores, this home offers both everyday convenience and timeless charm.

  Rene Church Century 21 Premiere Realty

  628 Moore Ave, Sikeston, MO 63801
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  /53

  $549,995

  • 4 Beds
  • 3 Baths
  • 3,770 Sq Ft

  106 Jennings Ln, Sikeston, MO 63801

  Experience elevated living in this beautifully crafted 3,770-square-foot residence ideally located just minutes from the conveniences of Sikeston. Offering four bedrooms and three full baths, this home was designed for both impressive entertaining and effortless daily living.The open-concept design creates a seamless flow between the living room, dining space, and chef-inspired kitchen. A

  Karen Chamberlain Poplar Bluff Realty Inc

  106 Jennings Ln, Sikeston, MO 63801
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  /4

  $15,000

  • Land
  • 0.16 Acre
  • $93,750 per Acre

  315 Jackson St, Sikeston, MO 63801

  Vacant residential lot ready for a buyer to build on. This is a 70 x 100 corner lot.

  Annie Harris Century 21 Premiere Realty

  315 Jackson St, Sikeston, MO 63801
• 

  

  /11

  $169,900

  • 4 Beds
  • 2 Baths
  • 2,101 Sq Ft

  502 Jaycee St, Sikeston, MO 63801

  This well-maintained four-bedroom, two-bath home offers plenty of room to grow, plus a versatile bonus space that can serve as a fifth bedroom, home office, playroom, or anything you envision. Situated on a desirable corner lot, the property features a fully fenced backyard—perfect for pets, gardening, or outdoor entertaining. Step inside to a warm and inviting layout, beginning with an eat-in

  Scott Harrison Delta Realty, LLC

  502 Jaycee St, Sikeston, MO 63801
• 

  

  /12

  $195,000

  • 3 Beds
  • 2 Baths
  • 1,421 Sq Ft

  112 N 6th St, Sikeston, MO 63801

  Step inside to find a bright and airy living space featuring a freshly painted interior and brand-new flooring throughout. The heart of the home is the spacious, open-concept kitchen—perfect for entertaining—boasting ample cabinetry and a layout that flows seamlessly into the dining and living areas. Both bathrooms have been updated, ensuring this home is move-in ready from day one.Situated

  Kaci Self Epique Realty

  112 N 6th St, Sikeston, MO 63801
• 

  

  /17

  $380,000

  • Land
  • 38 Acres
  • $10,000 per Acre

  00 Ellen Ave, Sikeston, MO 63801

  38 +/- acres of row-crop farmland with development potential located just outside Sikeston, Missouri. Property includes approximately 38 acres of tillable cropland plus 39 platted building lots in. Ideal for farmland investors, developers, or buyers seeking agricultural income, residential development, or long-term land investment. Level, open ground with easy access to Sikeston, highways, and

  Geoffrey Myers Living The Dream Inc.

  00 Ellen Ave, Sikeston, MO 63801
• 

  

  /38

  $315,000

  • 3 Beds
  • 2 Baths
  • 2,495 Sq Ft

  202 N Brushwick Ave, Sikeston, MO 63801

  Welcome home to this stunning single-level retreat on a huge lot, offering the perfect blend of space, comfort, and style. Step inside to a large open-concept floor plan filled with natural light from dramatic floor-to-ceiling windows, creating an airy, inviting atmosphere ideal for both everyday living and entertaining.The warm and inviting den features beautiful wood paneling, adding

  Lawren McMullan EDGE Realty, ERA Powered

  202 N Brushwick Ave, Sikeston, MO 63801
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  /36

  $250,000

  • 3 Beds
  • 3 Baths
  • 1,492 Sq Ft

  119 Depro Ave, Sikeston, MO 63801

  Newly remodeled and move-in ready just outside Sikeston! Sitting on a spacious corner lot with 0.7187 acres, this home gives you room to breathe and room to work. You’ll love the outdoor setup with a large shed plus a brand-new 30x40 pole barn, perfect for hobbies, storage, or a workshop. New roof, fresh updates, and space inside and out—this one checks all the boxes!

  Jessica Moore EXP Realty, LLC

  119 Depro Ave, Sikeston, MO 63801
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  /14

  $199,000

  • 3 Beds
  • 1 Bath
  • 1,296 Sq Ft

  312 Hardin St, Sikeston, MO 63801

  Completely remodeled and ready to move into! Located near the center of Sikeston, close to shopping, schools and banking. The roof is brand new with Owens Corning Duration 30-year shingles, along with LP Smartside on the outside. The kitchen has been competely redone with new cabinets and counter tops. All kitchen appliances are new and come with factory warranty. The wiring, lights, switches,

  Tim Merideth Century 21 Premiere Realty

  312 Hardin St, Sikeston, MO 63801
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  /21

  $259,900

  • 3 Beds
  • 2.5 Baths
  • 1,774 Sq Ft

  1811 State Highway Z, Sikeston, MO 63801

  This 3 bedroom, 2.5 bath home offers the perfect blend of space, privacy, and convenience. Situated on just over an acre +/- outside of city limits, you can enjoy peaceful country living while still being less than a 10 minute drive to town. The spacious layout provides comfortable living with thoughtful updates throughout. A standout feature is the shop, which offers over a thousand square feet

  Rachel Sitzes Poplar Bluff Realty Inc

  1811 State Highway Z, Sikeston, MO 63801
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  /32

  $149,900

  • 3 Beds
  • 2 Baths
  • 1,250 Sq Ft

  219 Petroleum St, Sikeston, MO 63801

  Take a look at this nice, clean, move-in ready home sporting a NEW ROOF! The charming front porch leads to an open living, kitchen & dining area. Primary bedroom with 3/4 bath, two additional bedrooms, one full bath and a one car attached carport, a 12x24 storage shed with walk-in door and garage door. This is the perfect size for a starter home or someone ready to downsize. Come and see for

  Rebecca Shaver C. Lawrence Realty LLC

  219 Petroleum St, Sikeston, MO 63801
• 

  

  /14

  $119,000

  • 3 Beds
  • 1 Bath
  • 1,080 Sq Ft

  318 Kendall St, Sikeston, MO 63801

  Welcome home to this fully remodeled 3-bedroom, 1-bath charmer, offering modern comfort and timeless style. Every detail has been thoughtfully updated, including fresh flooring, contemporary fixtures, new paint, and an inviting open layout that maximizes both light and space. All three bedrooms are generously sized, providing flexibility for family, guests, or a home office. The updated bathroom

  Lawren McMullan EDGE Realty, ERA Powered

  318 Kendall St, Sikeston, MO 63801
• 

  

  /72

  $665,000

  • 4 Beds
  • 4 Baths
  • 4,924 Sq Ft

  1304 Primrose Dr, Sikeston, MO 63801

  Built in 2019, this beautiful 4-bedroom, 4-bathroom home sits in one of Sikeston’s most desirable neighborhoods and offers a great mix of comfort, style, and modern features.You’ll love the brick-and-stone exterior and the inviting main-level living room with a cozy gas fireplace. Two bedrooms are located on the main floor, with two more upstairs—perfect for guests, kids, or a home office

  Lauren DeWitt EDGE Realty, ERA Powered

  1304 Primrose Dr, Sikeston, MO 63801
• 

  

  /12

  $264,000

  • 3 Beds
  • 2 Baths
  • 1,965 Sq Ft

  402 Garner St, Sikeston, MO 63801

  FIRST TIME ON THE MARKET !CUSTOM BUILT, ONE OWNER HOME, OPEN FLOOR PLAN WITH CUSTOM CABINETS, FLOORING , HUGE WALK IN SHOWER, INCLOSED SUNROOM ,ALL SITTING ON A LARGE CORNER LOT IN THE WESTVIEW SUBDIVISION AND SIKESTON SCHOOL DISTRICT .

  Tony McDonald McDonald Realty

  402 Garner St, Sikeston, MO 63801
• 

  

  /14

  $89,400

  • 2 Beds
  • 1 Bath
  • 1,000 Sq Ft

  406 W Gladys St, Sikeston, MO 63801

  Step inside this beautifully remodeled 2-bedroom, 1-bath home that’s move-in ready and full of modern updates! Fresh interior and exterior paint give the home a crisp, inviting look, while the brand-new flooring throughout adds warmth and style. Outside, the freshly painted exterior provides excellent curb appeal, and the manageable yard makes maintenance a breeze. Whether you’re a first-time

  Lawren McMullan EDGE Realty, ERA Powered

  406 W Gladys St, Sikeston, MO 63801
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  /21

  $1,000,000

  • 1,800 Sq Ft

  361 County Highway 405, Sikeston, MO 63801

  Exceptional Poultry Farm Opportunity with a 1,800 sqft 3 bed 2 bath home that was built in 2020. Presenting a rare opportunity to acquire a modern, income-producing poultry operation. This farm has been meticulously maintained and is available due to the owners’ retirement. Designed with efficiency and productivity in mind, the property offers state-of-the-art facilities and equipment to support

  Christy Lawrence C. Lawrence Realty LLC

  361 County Highway 405, Sikeston, MO 63801
• 

  /2

  $90,000

  • 3 Beds
  • 1 Bath
  • 1,077 Sq Ft

  849 William St, Sikeston, MO 63801

  Enjoy entertaining in this 3-bedroom, 1-bath home with a spacious yard and separate dining room. Updates like the new dryer plug-in, baseboard heaters, fresh interior paint, kitchen cabinets, and sink add modern convenience while keeping maintenance low. Plus, the covered carport provides protected parking. Set up a showing today!

  Tasha Cardin EXP Realty, LLC

  849 William St, Sikeston, MO 63801
• 

  /2

  $85,000

  • 2 Beds
  • 1 Bath
  • 1,144 Sq Ft

  848 Agnes St, Sikeston, MO 63801

  NEW ROOF! Welcome to this 2 bedroom, 1 bath home which includes a detached 2 car garage and partially fenced in yard. The bonus room has new siding, windows and roof which could serve as an additional bedroom, pleasant office, or additional living space. Some thoughtful upgrades you’ll love include new carpet, updated kitchen flooring, and fresh front and back doors. A must see!

  Tasha Cardin EXP Realty, LLC

  848 Agnes St, Sikeston, MO 63801
• 

  

  /38

  $344,500

  • 3 Beds
  • 3 Baths
  • 6,536 Sq Ft

  901 Moore Ave, Sikeston, MO 63801

  Do you like both indoor and outdoor space? This is the one for you. This home includes a large sunroom with ceiling fans located on the back of the house overlooking gorgeous landscaping. There's also outdoor space on the composite deck if you'd like a little sun. This nice brick home is on a corner lot in Sikeston's north end. Inside, the kitchen was recently remodeled with a nice island and

  Tim Merideth Century 21 Premiere Realty

  901 Moore Ave, Sikeston, MO 63801
• 

  

  /4

  $195,000

  • Land
  • 0.72 Acre
  • $270,833 per Acre

  116 Hospitality Dr, Sikeston, MO 63801

  Vacant, level lot. Not in the flood plain.

  Larry Lindsey Century 21 Premiere Realty

  116 Hospitality Dr, Sikeston, MO 63801

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